Back to Medicines A to Z. It's used to lower cholesterol if you've been diagnosed with high blood cholesterol. It's also taken to prevent heart disease, including heart attacks and strokes. Your doctor may prescribe atorvastatin if you have a family history of heart disease, or a long-term health condition such as type 1 or type 2 diabetes or rheumatoid arthritis. This medicine is available on prescription only.
It comes as tablets, including chewable tablets for people who have difficulty swallowing. Lipitor chewable tablets contain a substance called aspartame - check with your doctor before taking these if you have phenylketonuria a rare inherited disorder of protein metabolism. Take atorvastatin once a day. You can choose to take it at any time, as long as you stick to the same time every day.
Sometimes doctors may recommend taking it in the evening. This is because your body makes most cholesterol at night. If you're not sure when to take your medicine, ask a pharmacist or your doctor for advice.
Swallow atorvastatin tablets whole with a glass of water. If you've been given chewable tablets, you can chew them or swallow them whole with a glass of water.Bounded time series unit root tests
In children, the usual dose is 10mg to 20mg once a day. Your doctor will use your child's age to work out the amount of atorvastatin that's right for them. Your dose depends on the reason for taking it, your cholesterol levelsand what other medicines you're taking. Ask your doctor or pharmacist for advice if you're unsure how much to take. Don't reduce your dose without talking to your doctor first. If you occasionally forget to take a dose, take your next dose the next day at the usual time.
Never take 2 doses at the same time. Never take extra doses. If you often forget doses, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine. Like all medicines, atorvastatin can cause side effects in some people - and different statins affect people in different ways.
One rare but serious side effect is unexplained muscle aches and painstenderness or weakness. This can happen a few weeks or months after you first start taking this medicine. Talk to your doctor or a pharmacist if side effects are bothering you. They may recommend trying an alternative statin.
Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or don't go away:. Less than 1 in people may have some memory loss.
Talk to your doctor or pharmacist if this side effect bothers you. It usually goes away after you stop taking the medicine. Serious side effects when taking atorvastatin are rare and happen in less than 1 in 1, people. In rare cases, it's possible to have a serious allergic reaction anaphylaxis to atorvastatin.
These are not all the side effects of atorvastatin. For a full list see the leaflet inside your medicines packet. Atorvastatin isn't recommended during pregnancy or breastfeeding, as there's no firm evidence it's safe. Talk to your doctor if you want to get pregnant.Lipitor Atorvastatin is utilized in older people and young children who are a minimum of years old.
Atorvastatin Lipitor may result in a disorder that causes the demise of skeletal muscle cells, causing kidney problem. This problem might be usually appear in older adults as well as in patient who have kidney problems or badly managed thyroid issues. Patients may suffer from one or various Lipitor Atorvastatin common negative side effects that consist of minor to critical throughout their treatment.
Common negative side effects are minor body muscle ache, diarrhea and vomiting. Critical side effects are mysterious fever, serious muscles tiredness, tiredness, jaundice and inflammation.
Lipitor In highly uncommon cases, sufferers may possibly feel several dangerous side effects. Such as:. If sufferers feel any one of these negative effects, they are highly recommended to look for hospital treatment immediately. Serious sensitive side effects such as hives, trouble inhaling and inflammation of the lip area and tongue have also been claimed; this needs quick health care treatment. People who have unwanted side effects to Lipitor Atorvastatin tend to be encouraged to attempt some other sort of statin medicine instead of ending treatment with statins.
If you find difficulty with sudden or uncommon bleeding or bruising, this might be suggestive of a liver problem. You must talk to a medical professional immediately. If you find any of the following critical negative effects, avoid using your medicine and inform your doctor instantly or visit the nearby medical center. Related other Post:. October 19, 0. April 4, 0. October 11, 0.Como eliminar los gases intestinales rapido
Can Overdosing Lead to Tramadol High? April 9, 0.Medically reviewed by Drugs. Last updated on Oct 1, Applies to the following strengths: 5 mg mg; 10 mg mg; 5 mg mg; 10 mg mg; 5 mg mg; 10 mg mg; 5 mg mg; 10 mg mg; 2.
Initial dose: Amlodipine 5 mg-Atorvastatin 10 to 20 mg orally once a day Maximum dose: Amlodipine 10 mg-Atorvastatin 80 mg orally once a day Comments : -Individualized dose based on effectiveness and tolerance; select doses of amlodipine and atorvastatin independently.Xblnr field table in sap abap
Use: This combination drug is for patients for whom treatment with both amlodipine and atorvastatin is appropriate.
Administration Advice: -Take orally once a day at any time of day about the same time each day with or without food -Swallow whole; do not break before taking MISSED DOSE: -If you miss a dose take as soon as remembered, unless it has been more than 12 hours since last dose; if so, skip the missed dose and resume regular dosing; do not take 2 doses at the same time Monitoring : Atorvastatin : -Monitor liver enzymes before and during treatment. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Other brands: Caduet. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Skip to Content. Overview Side Effects Dosage Professional Interactions More Applies to the following strengths: 5 mg mg; 10 mg mg; 5 mg mg; 10 mg mg; 5 mg mg; 10 mg mg; 5 mg mg; 10 mg mg; 2.
Drug Status Availability Prescription only Rx.
Lipitor (Atorvastatin) Side Effects
Apotex Corp. Reddy's Laboratories, Inc. Greenstone LLC More…. Drug Class. Antihyperlipidemic combinations Miscellaneous antihypertensive combinations. Related Drugs.Medically reviewed by Sanjai Sinha, MD. Last updated on Jan 7, Atorvastatin is used together with diet to lower blood levels of "bad" cholesterol low-density lipoprotein, or LDLto increase levels of "good" cholesterol high-density lipoprotein, or HDLand to lower triglycerides a type of fat in the blood.
Atorvastatin is used to treat high cholesteroland to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. You should not take atorvastatin if you are pregnant or breastfeeding, or if you have liver disease.
Serious drug interactions can occur when certain medicines are used together with atorvastatin. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure.
Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Avoid eating foods that are high in fat or cholesterol. Atorvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.
Atorvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking this medicine and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine. Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking this medicine.Common acronyms in education
Atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism underactive thyroid.
Take atorvastatin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
Do not use this medicine in larger or smaller amounts or for longer than recommended. Atorvastatin is usually taken once a day, with or without food. Take the medicine at the same time each day. It may take up to 2 weeks before your cholesterol levels improve, and you may need regular blood tests.By proceeding, I accept the Terms and Conditions.
Hi, There are various studies comparing the different strengths of the two drugs, with respect to efficiency and side effects with different results. However during the first 12 weeks of one study simvastatin increased HDL cholesterol more than the comparative doses of atorvastatin, while producing slightly lower reduction in LDL cholesterol. At maximal dose comparison simvastatin 80mg and atorvastatin 80mg, HDL cholesterol lowering favoured simvastatin.
In another study efficacy of different strengths of atorvastatin were compared to different strength of simvastatin and found 40mg of simvastatin is equal to 80 mg of atorvastatin in lowering LDL cholesterol and increasing HDL Bottom line Simvastatin 40mg is equal to 80 mg atorvastatin.
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Home Premium Questions Home Is it safe to take lipitor 80 mg as an alternative for simvastatin 40 mg? Question: I am taking simvastatin 40 mg.
He says this would be of equal srength.Send the page " " to a friend, relative, colleague or yourself. We do not record any personal information entered above. Initially, 10 to 20 mg PO once daily. The daily dose may be given at any time during the day and without regard to meals. After dosage initiation or titration, lipid concentrations should be analyzed within two to four weeks.
In general, geriatric patients may have an increased cholesterol-lowering response to HMG-CoA reductase inhibitors. Coadministration of certain drugs with atorvastatin may need to be avoided or dosage adjustments may be necessary; review drug interactions. Dosage not established. Limited data suggest atorvastatin may improve inflammatory markers and left ventricular ejection fraction, especially in patients with dilated cardiomyopathy.
However, clinical practice guidelines for the treatment of heart failure in adults recommend statins only in patients with a recent or remote history of myocardial infarction or acute coronary syndrome to prevent symptomatic heart failure and cardiovascular events.
Is it safe to take lipitor 80 mg as an alternative for simvastatin 40 mg?
Patients in the control group started atorvastatin at an average of 95 weeks post-transplant. Significantly fewer patients in the early atorvastatin group developed graft coronary artery disease compared to the control group 2 vs.
In addition, patients in the early atorvastatin group had fewer episodes of treated rejection in the first year post-transplant compared to the control group 0. Active liver disease or unexplained persistent transaminase elevations are contraindications to the use of atorvastatin.
Renal impairment has no influence on atorvastatin plasma concentrations or LDL cholesterol reductions. No dosage adjustments are needed. Intermittent hemodialysis Hemodialysis does not enhance the clearance of atorvastatin or its metabolites ; no dosage adjustment is needed.
NOTE: Patients receiving atorvastatin therapy should also be placed on a standard cholesterol-lowering diet, and this diet should be continued throughout therapy. Serum lipoprotein concentrations should be determined periodically and dosage adjusted according to individual response and established NCEP treatment guidelines. Administer orally at about the same time each day, at any time of day. Atorvastatin may be administered orally without regard to meals.
Avoid grapefruit juice to avoid potential increases in drug serum concentrations. Atorvastatin is contraindicated in patients with atorvastatin hypersensitivity or hypersensitive to any components of the product selected.
Atorvastatin is contraindicated in patients with active hepatic disease including cholestasis, hepatic encephalopathy, hepatitis, and jaundice or unexplained persistent elevations in serum aminotransferase concentrations. Elevated hepatic transaminases have been reported in patients receiving HMG-CoA reductase inhibitors; these abnormalities were not associated with cholestasis and did not appear to be associated with treatment duration.
Assess liver enzymes prior to initiation of atorvastatin therapy and repeat as clinically indicated. After extensive data review, the FDA concluded that the risk of serious liver injury is very low and routine periodic monitoring of liver enzymes has not been effective in detection or prevention of serious hepatic injury. If an alternate etiology is not found, do not restart atorvastatin. Myopathy is a potential serious side effect of HMC-CoA reductase inhibitors; rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported with atorvastatin and other drugs in this class.
Atorvastatin therapy should be discontinued if myopathy is diagnosed or suspected or if a patient who develops marked elevations in CPK or rhabdomyolysis. Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Atorvastatin may be contraindicated or temporarily withheld in conditions that can cause decreased renal perfusion since renal failure is possible if atorvastatin-induced myopathy and rhabdomyolysis occurs.
The risk of developing myopathy is also increased when HMG-CoA reductase inhibitors are used in combination with selected drugs e. Atorvastatin should be used with caution in organ transplant and other patients receiving immunosuppressant therapy such as cyclosporine because of an increased risk of rhabdomyolysis and renal failure; lower initial and maximum doses of atorvastatin are recommended for such patients.
Renal disease has no influence on atorvastatin plasma concentrations or LDL cholesterol reductions; dosage adjustments are not needed in patients with renal impairment. If atorvastatin is initiated in a patient with diabetes mellitus, increased monitoring of blood glucose control may be warranted. Increased hemoglobin A1C, hyperglycemia, and worsening glycemic control have been reported during therapy with HMG-CoA reductase inhibitors. Because the use of statins has been associated with significant benefit for cardiovascular risk reduction and all-cause mortality at comparable rates in diabetic and non-diabetic patientsno changes to clinical practice guidelines have been recommended in either population.
However, the increased risk of diabetes mellitus should be considered when initiating atorvastatin therapy in patients at low risk for cardiovascular events and in patient groups where the cardiovascular benefit of statin therapy has not been established.Drug information provided by: IBM Micromedex. Along with its needed effects, a medicine may cause some unwanted effects.
Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. Other side effects not listed may also occur in some patients.
If you notice any other effects, check with your healthcare professional.
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